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Welcome

Motivated by diseases arising from the misregulation of proteins and nucleic acids, our biophysical approach makes connections between molecular mechanism and cellular function through time-resolved spectral imaging at multiple scales, from in vitro to single cell to whole organism.

We are part of the Chemistry Department at Yale University.

Recent Publications

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G. Hoy and C.M. Davis

Multispectral analysis graphical user interface for ratiometric analysis and background correction

Chem. -Methods 2026, 6, e70167.

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H.B. Castillo, C.M. Davis

Optical photothermal infrared imaging of fatty acid esterification in the ER of living cells

Sci. Adv. 2026, 12 (28) eaed6477.

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E. Knab, U. Tahir and C.M. Davis       

Mimetics of in-cell and subcellular crowding and solvation for protein folding

Biochem. Soc. Trans.  2026, 54 (4), 413-425.

Current and Past Funding Sources

We acknowledge the funding agencies that made this work possible

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© 2019 Davis Lab

Davis Lab, Yale University

Department of Chemistry

255 Prospect St, KCL 108

New Haven, CT 06511

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